Optimization of photon beam energy in the treatment of thyroid cancer in the presence of gold and silver nanoparticles

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عنوان دوره: اولین دوره بین المللی و بیست و هشتمین دوره ملی (1400)
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چکیده
Today, the use of nanoparticles in radiotherapy is recommended and Increases survival and reduces local attack as well as DNA damage of cancer cells., in this study, to investigate the effect of radiation sensitivity, parameters such as radiation energy and type of nanoparticles in the thyroid tissue simulated in MCNP5 code were investigated. The results show that in the presence of nanoparticles the absorption dose within the tumor increases. The highest dose improvement coefficient was obtained in the presence of gold nanoparticles in energies of 64 to 66 keV with a value of 158% and in the presence of silver nanoparticles in energies of 68 keV with a value of 192%. At optimum energy, silver nanoparticles are more effective than gold nanoparticles in terms of dose increase.
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