Dosimetric comparison between low dose rate and high dose rate brachytherapy for prostate cancer: a Monte Carlo study
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عنوان دوره: اولین دوره بین المللی و بیست و هشتمین دوره ملی (1400)
This study performs a dosimetric comparison between low-dose-rate brachytherapy with I-125 and single-fraction high-dose-rate brachytherapy with Ir-192 for the treatment of prostate cancer. The dose distributions in the prostate as well as the delivered dose to the organs at risk surrounding the prostate were obtained by Geant4 Monte Carlo toolkit. The results indicate that very low-activity HDR brachytherpay with Ir-192 sources delivers a lower dose to the OARs than I-125 LDR brachytherapy with equal seed activities. Therefore, the significance of performing high-activity HDR brachytherapy in a fractionation scheme is further emphasized.
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