Investigating the relationship between Anatomical changes and organ at risk dose in magnetic resonance imaging (MRI)-guided carbon-ion radiotherapy (MRgCT) of prostate cancer

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عنوان دوره: اولین دوره بین المللی و بیست و هشتمین دوره ملی (1400)
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چکیده
In the present study, first, the anatomical changes impact on dose variations in prostate and bladder organs (as an organ at risk) was assessed. Second, variation in prostate and bladder dose due to a set-up error for a potential method of magnetic resonance imaging-guided carbon-ion radiotherapy (MRgCT) of prostate cancer was investigated. For this purpose, carbon-ion beams perpendicular to a pelvis phantom in which 1.5 T transverse magnetic field was applied were simulated using the FLUKA code. To assess the effect of anatomical changes, changes in dose of the bladder, prostate, and rectum, as well as set-up error were investigated. The results show that anatomical changes lead to important change of the dose in MRgCT prostate cancer.
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