A Monte Carlo investigation of the dose distribution for new I-125 by GEANT4

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عنوان دوره: اولین دوره بین المللی و بیست و هشتمین دوره ملی (1400)
Brachytherapy is a special type of radiation therapy in which the source of radiation, such as seed(s), is placed near or inside a tumor. In this study, at first we simulated and validated I-125 source (model 6711) seed, as a common source in brachytherapy, according to the TG-43U1 recommendation, by GEANT4 Monte Carlo toolkit. Moreover, we simulated a new I-125 seed contains a cylindrical Ag+Al2O3 marker and calculated its radial dose and anisotropy function. The source validation show that GEANT4 Monte Carlo toolkit produces accurate results for dosimetric parameters of the I-125 seed with choosing the appropriate physics list. On the other hand, results show a similarity between calculated dosimetric parameters of the I-125 seed (6711) and the new source, with a percentage difference about 5%.
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