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عنوان دوره: اولین دوره بین المللی و بیست و هشتمین دوره ملی (1400)

Radiosensitization using high atomic number nanoparticles (NPs) have been recently investigated in various radiation therapy modalities. In this work we investigated the dose nehancement effect of Au, Pb, Ti, Fe, Ag, Bi, Gd and Ta NPs in brachytherapy of breast cancer by the AccuBoost system by using Monte Carlo simulations. The results showed Bi, Pb and Au to be the most effective while suggested the smallest NP size and highest concentration of NPs in tumour to give the highest dose enhancement resulting in the shortest treatment time.

AccuBoost؛ nanoparticles؛ MIRD phantom؛ MCNPX؛ Brachytherapy؛ 192Ir source